Hamlet had it easy. All he had to figure out was whether “to be or not to be?” — a one-time dilemma, at least if he chose “not to be.”
My own quandary, though admittedly relatively frivolous, is a continuing puzzlement that challenges me repeatedly, not on a daily basis but whenever I plan a trip. My soul-searching question, which I am compelled to ask of every item in my closets and drawers, is “to pack or not to pack?” You’d think that it would get easier every time. Wrong. If anything, it seems to get harder.
Though I travel fairly frequently, I still haven’t figured out what to take with me. I can be certain of only two things: If I leave it home, I’ll wish I had it; if I pack it, I’ll wish I hadn’t.
Danish backpackers in front of the Vienna State Opera, Wikipedia Commons. (Editor’s Note: Rose told us that this is not her packing style)
The pioneers who crossed the Great Plains were lucky. They could stuff all their stuff into the old Conestoga wagon. Come to think of it, they didn’t have much stuff, as opposed to their wealthy descendants who crossed the Atlantic on luxury liners who did have a lot of stuff, but didn’t have a packing problem. They simply had their personal maids transfer the contents of their closets and chests to spacious steamer trunks.
Today most of us also have lots of stuff, but no personal maids; and we usually travel long distances on airships instead of steamships. Goodbye steamer trunk, hello dilemma.
The urge to overpack must be in our genes. It’s hard to stifle. If only we could remember that last trip when we had to schlep those heavy bags from home to the departure airport, from the arrival airport to the hotel-or, in the case of a multi-destination trip, to and from many hotels-the ultimate nightmare! Worse yet, unpacking at each stop along the way can consume hours which should be spent seeing the sights and mingling with the locals. Be honest. Wouldn’t you rather be floating on a gondola while Rudolfo serenades you?
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Attempts to Curtail Sexual and Reproductive Health and Rights: Look At the 2015 Record In States
April 2, 2015
By the end of the first quarter of the year, legislators had introduced 791 provisions related to
sexual and reproductive health and rights. Nearly 42% of these provisions (332 provisions) seek to restrict access to abortion services; abortion restrictions have been introduced in 43 states. By April 1, 53 abortion restrictions had been approved by a legislative chamber, and nine had been enacted. Many of the new abortion restrictions enacted this year would either limit the use of medication abortion (Arkansas and Idaho) or ban abortion at 20 weeks postfertilization (West Virginia), a disturbing combination of attempts to curtail access in both the early and later months of pregnancy, potentially leaving women with fewer options and a greatly reduced time frame to get the care they need.Abortion opponents’ assault on medication abortion, a procedure that likely has helped women obtain abortion care earlier in pregnancy and now accounts for nearly one-quarter of all non-hospital abortions, is continuing apace in 2015. So far this year, Arkansas enacted a new law requiring abortion providers to follow the outdated protocol included in the FDA-approved labeling for medication abortion that is more expensive, carries a higher risk of side effects, and requires more clinic visits than does the widely used evidence-based protocol; in addition, the FDA regimen can only be used during the first 49 days of pregnancy, compared with 63 days for the evidence-based protocol. North Dakota, Ohio and Texas have similar laws (see Medication Abortion).
In addition, Arkansas adopted two measures banning telemedicine for medication abortion; one was an independent bill and the other was included in the state’s law governing the use of telemedicine in general. Idaho enacted a similar ban on using telemedicine for abortions bringing to 18 the number of states that ban the use of telemedicine for the procedure (see Medication Abortion).
At the same time, several states are also moving toward restricting access to abortion services later in pregnancy. The West Virginia legislature overrode a veto by Gov. Earl Ray Tomblin (D) to enact a ban on abortion starting at 20 weeks postfertilization; similar measures are pending in seven other states. Including West Virginia, 14 states ban abortions at 20 weeks postfertilization (see State Policies on Later Abortions). In addition, several states are considering a new type of restriction that uses graphic terminology in an attempt to limit how a second-trimester abortion can be provided. These measures, which are designed to ban most abortions after the first trimester, have been approved by both chambers of the Kansas legislature, one chamber in Oklahoma and are pending in Missouri and South Carolina. (Kansas Gov. Sam Brownback (R) is expected to sign his state’s measure in early April.)
Legislators in 21 states have introduced 43 provisions seeking to impose targeted regulations on abortion providers (see TRAP). Two states have enacted new provisions. Arkansas enacted two provisions, a measure that requires specific and costly procedures for the disposal of fetal remains and a requirement that medication abortion providers have admitting privileges at a local hospital. Arizona enacted a measure that tightens requirements related to abortion providers’ admitting privileges. Additional measures passed by one legislative chamber in four states seek to make existing TRAP requirements more stringent by increasing inspection requirements (Missouri and Oklahoma); permitting the state to deny a clinic license if a previous license was revoked, suspended or terminated for any reason including administrative (Texas); and expanding the laws’ reach to physicians who provide five or more abortions annually in their private offices (Indiana).
Finally, legislators in 16 states have introduced state versions of the Religious Freedom Restoration Act (RFRA). The US Supreme Court relied on the federal version of the law in its decision in Burwell v. Hobby Lobby to justify permitting businesses to refuse to provide contraceptive coverage. Indiana Gov. Mike Pence (R) signed the bill mirroring RFRA into law in late March, provoking an enormous public outcry. (The outcry has led the Governor and the legislature to reevaluate the law.) Both chambers of the Arkansas legislature and one chamber in Georgia and Wyoming have passed similar measures. Notably, the uproar over these measures has centered on their potential to sanction discrimination against gay individuals. However, the potential impact on contraceptive coverage — and reproductive health more broadly — has received little, if any, attention.
About the Guttmacher Institute: Now in its fifth decade, the Guttmacher Institute continues to advance sexual and reproductive health and rights through an interrelated program of research, policy analysis and public education designed to generate new ideas, encourage enlightened public debate and promote sound policy and program development. The Institute’s overarching goal is to ensure the highest standard of sexual and reproductive health for all people worldwide.
The Institute produces a wide range of resources on topics pertaining to sexual and reproductive health, publishes two peer-reviewed journals, Perspectives on Sexual and Reproductive Health and International Perspectives on Sexual and Reproductive Health, and the public policy journal Guttmacher Policy Review. In 2013, the Institute was awarded a prestigious Population Center grant by the National Institutes of Health (NIH) in support of the Guttmacher Center for Population Research Innovation and Dissemination. Guttmacher is one of only two non-university-based institutions out of the two dozen receiving such funding.
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The Scout Report for a Spring Break: Loneliness; On Broadway; Biomedical Engineering; The Most Dangerous World Ever?; Killer Digital Libraries; Landscape Architecture; The Muse, a Free Job Hunting Service
On Broadway: Ed Ruscha holding his book Every Building on the Sunset Strip, 1967. © Ed Ruscha. Image courtesy of Jerry McMillan and Craig Krull Gallery, Santa Monica. © Jerry McMillan.
The Risks of Being Lonely
Loneliness and social isolation linked to early mortality
http://www.medicalnewstoday.com/articles/290934.phpLoneliness Can Be Deadly, Study Says
http://www.youthhealthmag.com/articles/11844/20150317/loneliness-can-be-deadly-study-says.htmWhy Loneliness Is A Growing Public Health Concern — And What We Can Do About It
http://www.huffingtonpost.com/2015/03/21/science-loneliness_n_6864066.html?utm_hp_ref=scienceYou Asked: How Many Friends Do I Need?
http://time.com/3748090/friends-social-health/?iid=time_speedResearchers Study “Super Seniors” for Clues to their Longevity
http://canadajournal.net/health/researchers-study-super-seniors-clues-longevity-23991-2015/Feeling Lonely Tonight? 7 Strategies to Combat Loneliness
http://psychcentral.com/blog/archives/2013/11/08/feeling-lonely-tonight-7-strategies-to-combat-loneliness/The statistics on loneliness are show stopping: one in five Americans are persistently lonely; loneliness has been linked to depression, anxiety, and suicide; and, despite an increase in social media, loneliness has nearly doubled over the last 30 years. This month Perspectives on Psychological Science published a special issue on the topic of loneliness and what researchers found made headlines around the world. One study showed that persistent loneliness is a bigger killer than obesity. Another zeroed in on the biological underpinnings of the condition. A third examined group therapy, individual therapy, and community interventions, and found all three to be effective interventions for helping the lonely. Now that we know the true impacts of loneliness, researchers think it’s time to treat it as a serious public health issue – and for those reading the research, it’s almost certainly time to reach out to others and make a connection.
The first link takes readers to Medical News Today, which offers coverage of the new studies as well as a call to treat loneliness as a public health risk. The second and third links, from Youth Health Magazine and the Huffington Post, expand the coverage with quotes from researchers and experts in the field. Next, Time‘s Mark Heid uses Dr. Robin Dunbar’s research to ask how many friends we actually need. The answer? Just a few, as long as they are close confidants. The fifth link navigates to a recent article about ‘super seniors,’ those are older people who stay happy and healthy due to a host of interrelated factors – including staying social, active, and busy. Finally, the last link takes readers to a blog post on how to alleviate loneliness, including suggestions like “nurture others” and “work hard to get your sleep.”
Society for the Teaching of Psychology
The Society for the Teaching of Psychology is a great find for anyone teaching this essential social science in high school, community college, or four year higher educational institutions — or for anyone with a passion for the topic. From the homepage, readers may survey the presidential welcome, or explore sections such as STP News and the GSTA (Graduate Student Teaching Association) Blog as ways to stay connected on the cutting edge practices currently used in psychology education. The Resources tab covers topics that range from diversity to teaching competencies. The Teaching Resources section is especially helpful, as it links to presentations, PDFs, and documents about a range of topics, all with the idea of informing educators. Date of publications vary from 1990 to present day, and cover topics like “Educating Students about Plagiarism” and “Psychology of Peace and Mass Violence — Instructional Resources.”
John Singer Sargent’s Intimate Portraits of Artists and Friends: Witty and Radical
The National Portrait Gallery in London is hosting works by one of the world’s most celebrated portrait painters, John Singer Sargent. Organized in partnership with the Metropolitan Museum of Art in New York, the exhibition brings together, for the first time, a collection of the artist’s intimate and informal portraits of his impressive circle of friends, including Robert Louis Stevenson, Claude Monet and Auguste Rodin.The exhibition, Sargent: Portraits of Artists and Friends, shown until 25 May 2015, explores the artist as a painter at the forefront of contemporary movements in the arts, music, literature and theater, revealing the depth of his appreciation of culture and his close friendships with many of the leading artists, actors and writers of the time.
La Carmencita (left), by John Singer Sargent, c 1890. Photograph: National Portrait Gallery, London
Ellen Terry as Lady Macbeth (right) by John Singer Sargent. Oil on Canvas, Collection: Tate
Bringing together remarkable loans, some rarely exhibited, from galleries and private collections in Europe and America, the exhibition will follow Sargent’s time in Paris, London and Boston as well as his travels in the Italian and English countryside. Musée Rodin, the Fine Arts Museums of San Francisco, Musée d’Orsay, the Art Institute of Chicago and the Minneapolis Institute of Arts are amongst the institutions that are lending works.
Sargent’s portraits of his friends and contemporaries were rarely commissioned and allowed him to create more experimental works than was possible in his formal portraiture. His sitters are depicted in informal poses, sometimes in the act of painting or singing, resulting in a collection of highly-charged, original portraits. These paintings form a distinctive strand in Sargent’s work which is noticeably more intimate, witty and radical, and, when brought together in the exhibition, will challenge the conventional view of the artist.
Key exhibits include the only two surviving portraits Sargent painted of his friend and novelist Robert Louis Stevenson, which will be displayed together for the first time since they were painted in the 1880s. Also reunited in the exhibition will be Sargent’s portraits of the Pailleron family, drawn from collections in Paris, Washington DC and Iowa. The bohemian writer Édouard Pailleron and his wife were among Sargent’s earliest French patrons, and to whom the young artist owed much of his early success. Their individual portraits will be displayed alongside Sargent’s portrait of their children, Édouard and Marie-Louise, for the first time in over a century.
Other exhibition highlights include Sargent’s important portrait of his master Carolus-Duran (1879), which played a pivotal role in the development of his career after it was praised in the 1879 Paris Salon; his charcoal drawing of the celebrated poet William Butler Yeats (1908); and three of his greatest theatrical portraits painted between 1889 and 1890: Ellen Terry as Lady Macbeth, Edwin Booth and La Carmencita, the wild Spanish dancer.
Two sections in the exhibition will focus on the portraits and plein-air figure scenes he painted during time spent in the artistic community in the village of Broadway in rural Worcestershire, and those he painted after 1900 on his travels to the Alps and southern Europe. Sitters include Sargent’s familiars such as the artists Jane and Wilfred de Glehn who accompanied him on his sketching expeditions to the continent and often feature as a pair in his work. In these paintings Sargent explored the making of art (his own included) and the relationship of the artist to the natural world.
John Singer Sargent, Dr. Pozzi at Home, 1881. Oil on canvas. 79 3/8 x 40 1/4 in. (201.6 x 102.2 cm). Hammer Museum, Los Angeles.How Severe is the Shortage of Substance Abuse Specialists?
The Substance Abuse and Mental Health Services Administration (SAMHSA) is the agency within the US Department of Health and Human Services that leads public health efforts to advance the behavioral health of the nation. SAMHSA’s mission is to reduce the impact of substance abuse and mental illness on America’s communities.
By Christine Vestal, Stateline
The number of people with insurance coverage for alcohol and drug abuse disorders is about to explode at a time there’s already a severe shortage of trained behavioral health professionals in many states.
Until now, there’s been no data on just how severe the shortage is and where it’s most dire. Jeff Zornitsky of the health care consulting firm Advocates for Human Potential (AHP) has developed the first measurement of how many behavioral health professionals are available to treat millions of adults with a substance use disorder, or SUD, in all 50 states.
Zornitsky’s “provider availability index” – the number of psychiatrists, psychologists, counselors and social workers available to treat every 1,000 people with SUD – ranges from a high of 70 in Vermont to a low of 11 in Nevada. Nationally, the average is 32 behavioral health specialists for every 1,000 people afflicted with the disorder. No one has determined what the ideal number of providers should be, but experts agree the current workforce is inadequate in most parts of the country.
“Right now we’re in a severe workforce crisis,” said Becky Vaughn, addictions director for the industry organization National Council for Behavioral Health. The shortage has consequences, she said. “When people need help for addictions, they need it right away. There’s no such thing as a waiting list. If you put someone on a waiting list, you won’t be able to find them the next day.”
The shortage of specialists threatens to stall a national movement to bring the prevention and treatment of SUD into the mainstream of American medicine at a time when millions of people with addictions have a greater ability to pay for treatment thanks to insurance.
The Affordable Care Act for the first time requires all insurers, including Medicaid, to cover the treatment of drug and alcohol addiction. In the past, Medicaid covered only pregnant women and adolescents in most states. Private insurance either didn’t pay for treatments or paid so little that most people could not afford to make up the difference.
For anyone with insurance coverage, the Mental Health Parity and Addiction Equity Act ensures that the duration and dollar amount of coverage for substance use disorders is comparable to coverage for medical and surgical care. Together, the two federal laws are expected to make billions of dollars available to the behavioral health care market.
Of the estimated 18 million adults potentially eligible for Medicaid in all 50 states, at least 2.5 million have substance use disorders. Of the 19 million uninsured adults with slightly higher incomes who are eligible for subsidized exchange insurance, an estimated 2.8 million struggle with substance abuse, according to the most recent national survey by the US Substance Abuse and Mental Health Services Administration.
Although the federal government has acknowledged the scarcity of treatment specialists, it has failed to quantify and assess it. Other fields of health care, including mental health and primary care, are tracked by the US Health Resources and Services Administration to determine which communities are “underserved.” Without this information, it is hard to know where more behavioral health specialists are needed and when the supply of providers is expanding or shrinking in any given region.
That’s where AHP’s Zornitsky steps in. Using data from the US Department of Labor’s Bureau of Labor Statistics on the current size of the labor force and its projected growth, plus Department of Health and Human Services data on the prevalence of SUD among adults, he approximates the relative adequacy of the addiction treatment workforce in each state.
“It is not perfect,” Zornitsky said of the index, “but it’s a consistent, state-based measure that allows for comparisons and tracking over time.”
When Planning a Visit To Washington DC: Restoring the United States Capitol Dome and Rotunda
“We have built no temple but the Capitol. We consult no common oracle but the Constitution.”
— Rufus Choate
The United States Capitol Dome, symbol of American democracy and world-renowned architectural icon, was constructed of cast iron more than 150 years ago. The Dome has not undergone a complete restoration since 1959-1960 and due to age and weather is now plagued by more than 1,000 cracks and deficiencies.
The Architect of the Capitol began a multi-year project to repair these deficiencies, restoring the Dome to its original, inspiring splendor and ensuring it can safely serve future generations of visitors and employees as the roof of the Capitol.
“As stewards of the Capitol for the Congress and the American people, we must conduct this critical work to save the Dome,” said Architect of the Capitol Stephen T. Ayers, FAIA, LEED AP. “From a distance the Dome looks magnificent, thanks to the hard-work of our employees. On closer look, under the paint, age and weather have taken its toll and the AOC needs to make repairs to preserve the Dome.”
Following a full and open competitive bidding process, a contractor was selected to perform the Dome Restoration Project. The AOC will supervise the project to ensure it remains on time and on budget. The project was awarded in November 2013 and preparation work began in January 2014.
To protect the public during this project, a canopy system in the shape of a doughnut will be installed in the Capitol Rotunda. The configuration allows the Apotheosis of Washington mural, in the eye of the Rotunda, to be visible during the restoration process. To facilitate the installation of the canopy system, the Rotunda was closed from April 12 to April 28, 2014.
Following installation of the safety netting, a scaffold system that will surround the exterior of the Dome has been installed. Scaffold towers and scaffold bridging will also be constructed on the West Front of the US Capitol Building (the National Mall side) to help move materials to the work areas.
Scaffolding and Restoring Phase
The Dome Restoration Project team is currently working behind the large containment area to remove lead paint and apply primer before repairing the cracks. As additional containment areas are mounted, the Architect of the Capitol is now using a new fabric to reduce the possibility of tearing during installation that can be caused by high wind gusts. This new material has a pink hue and will be used for most of the remaining containment areas, except near the top of the Dome where the plastic material would be better suited for enclosure at that location.
FAQ: The House Passes A Bill To Fix Medicare’s Doctor Payments. What’s In It?
The troubled payment formula for Medicare physicians is one step closer to repeal.
The House last (March 26) Thursday overwhelmingly passed legislation to scrap Medicare’s troubled physician payment formula, just days before a March 31 deadline when doctors who treat Medicare patients will see a 21 percent payment cut. The Senate is expected to consider the measure when it returns to work April 13 after its two-week recess.
According to a summary of the bill, unveiled by Republican and Democratic committee leaders earlier last week, the current system would be scrapped and replaced with payment increases for doctors for the next five years as Medicare transitions to a new system focused “on quality, value and accountability.”
There’s enough in the wide-ranging deal for both sides to love or hate.
Senate Democrats have pressed to add to the proposal four years of funding for an unrelated program, the Children’s Health Insurance Program, or CHIP. The House package extends CHIP for two years. In a March 21 statement, Senate Finance Democrats said they were “united by the necessity of extending CHIP funding for another four years” but others have suggested they may support the package.
Some senators have also raised concerns about asking Medicare beneficiaries to pay for more of their medical care, the impact of the package on women’s health services and cuts to Medicare providers.
In a letter to House members before Thursday’s vote, the seniors group AARP said the legislation places “unfair burdens on beneficiaries. AARP and other consumer and aging organizations remain concerned that beneficiaries account for the largest portion of budget offsets (roughly $35 billion) through greater out-of-pocket expenses” on top of higher Part B premiums that beneficiaries will pay to prevent the scheduled cut in Medicare physician payments.
Some Democratic allies said the CHIP disagreement should not undermine the proposal. After the House approved the SGR package by a vote of 392-37, Ron Pollack, executive director of the consumers group Families USA, urged the Senate to “adopt a CHIP funding bill as soon as possible. Families USA believes that a four-year extension is preferable to two years. We also know that time is of the essence, and it is crucial that the Senate act quickly.”
Some GOP conservatives and Democrats are unhappy that the package isn’t fully paid for, with policy changes governing Medicare beneficiaries and providers paying for only about $70 billion of the approximately $200 billion package. The Congressional Budget Office Wednesday said the bill would add $141 billion to the federal deficit.
For doctors, the package offers an end to a familiar but frustrating rite. Lawmakers have invariably deferred the cuts prescribed by a 1997 reimbursement formula, which everyone agrees is broken beyond repair. But the deferrals have always been temporary because Congress has not agreed to offsetting cuts to pay for a permanent fix. In 2010, Congress delayed scheduled cuts five times. In a statement Sunday, the American Medical Association urged Congress “to seize the moment” to enact the changes and since expressed disappointment that the Senate will not act on the measure before the cut takes effect April 1.
Here are some answers to frequently asked questions about the proposal and the congressional ritual known as the doc fix.
Q: How did this become an issue?
The Medicare Payment Advisory Commission (MedPAC), which advises Congress, says the SGR is “fundamentally flawed” and has called for its repeal. The SGR provides “no incentive for providers to restrain volume,” the agency said.
Q. Why haven’t lawmakers simply eliminated the formula before?
Money is the biggest problem. An earlier bipartisan, bicameral SGR overhaul plan produced jointly by three key congressional committees would cost $175 billion over the next decade, according to the Congressional Budget Office. While that’s far less than previous estimates for SGR repeal, it is difficult to find consensus on how to finance a fix.
For physicians, the prospect of facing big payment cuts is a source of mounting frustration. Some say the uncertainty has led them to quit the program, while others are threatening to do so. Still, defections have not been significant to date, according to MedPAC.
In a March 2014 report, the panel stated that beneficiaries’ access to physician services is “stable and similar to (or better than) access among privately insured individuals ages 50 to 64.” Those findings could change, however, if the full force of SGR cuts were ever implemented.
“The flawed Sustainable Growth Rate (SGR) formula and the cycle of patches to keep it from going into effect have created an unstable environment that hinders physicians’ ability to implement new models of care delivery that could improve care for patients,” said AMA president Dr. Robert M. Wah. “We support the policy to permanently eliminate the SGR and call on Congress to seize the moment and finally put in place reforms that will foster innovation and put us on a path towards a more sustainable Medicare program.”
Q: What are the options that Congress is looking at?
The House package would scrap the SGR and give doctors a 0.5 percent bump for each of the next five years as Medicare transitions to a payment system designed to reward physicians based on the quality of care provided, rather than the quantity of procedures performed, as the current payment formula does.
The measure, which builds upon last year’s legislation from the House Energy and Commerce and Ways and Means Committees and the Senate Finance Committee, would encourage better care coordination and chronic care management, ideas that experts have said are needed in the Medicare program. It would give a 5 percent payment bonus to providers who receive a “significant portion” of their revenue from an “alternative payment model” or patient-centered medical home. It would also allow broader use of Medicare data for “transparency and quality improvement” purposes.
More States Demand Notification to Use Biosimilar Drugs
By Michael Ollove, Stateline
Without the medicine Rachelle Crow takes for her rheumatoid arthritis, the 29-year-old Michigan woman’s face would frequently feel as if it were engulfed in flames. She would barely be able to crawl out of bed. She would have trouble opening or closing her fists or lifting her 3-year-old daughter.
Crow can do all those things thanks to Cimzia, one of a highly complex, usually expensive class of drugs known as biologics that derive from living organisms. Cimzia is recommended for women, like Crow, who are trying to get pregnant.
This cross-section of a blood vessel illustrates a condition called chronic allograft vasculopathy (CAV), a major factor limiting long-term survival following heart transplants. Image: Nathalie Accart-Gris/Novartis
What keeps her up at night is a fear that a pharmacy could substitute a cheaper, not-quite identical drug for Cimzia without her or her doctor’s knowledge. It’s not only a return of her worst symptoms that she worries about. “If another medicine were substituted without telling me or my doctor, it could put my pregnancy at risk,” she said.
Fears like Crow’s have helped propel legislative attempts in many states this year to make sure that patients and doctors are notified whenever imitations deemed “interchangeable” by the US Food and Drug Administration (FDA) are substituted for brand-name biologics. Already, Colorado has passed a notification law, and Utah has revised its earlier law. More than a dozen states are considering comparable measures.
Notification bills began popping up in states two years ago, but most were defeated in the face of opposition from manufacturers of biologic copies, which are called biosimilars, and from organizations representing pharmacists, who objected to the extra workload notification requirements might entail.
Thirteen states killed or tabled bills the last two years. Only eight states (Delaware, Florida, Indiana, Massachusetts, North Dakota, Oregon, Virginia and Utah) ended up enacting laws. A ninth, California, passed a bill through the legislature only to see it vetoed by Democratic Gov. Jerry Brown.
But the legislative climate for enacting notification law is different now that biosimilars are finally coming on the market.
Earlier this month, the FDA for the first time approved a biosimilar. Manufactured by Sandoz, a division of the pharmaceutical company Novartis, Zarxio is the biosimilar version of Amgen Inc.’s anti-infection biologic Neupogen. Neupogen, which was licensed in 1991, is used for certain cancer patients undergoing chemotherapy or bone marrow transplantation among others.
The FDA confirms that at least three other biosimilars are awaiting FDA approval. Many others are in development.
The arrival of biosimilars has been eagerly awaited by patients and health consumer groups.
For Julie Wiles, a Houston resident with rheumatoid arthritis, biosimilars couldn’t come soon enough. Through a pharmacy assistance program, she was able to get the biologic Enbrel.
“I did not have flare-ups or joint pain” after starting on the Enbrel, Wiles said. “I could get up in the morning. The biologic was literally changing my life. I felt normal.”
But after six or seven months, the program was no longer able to supply her Enbrel, and her insurance company would not pay for the drug.
“That’s when I learned it would cost me $2,500 an injection, and I needed an injection every week,” Wiles said. She went back on conventional medications, which don’t control her symptoms nearly as well.
5th White House Science Faire; The Theme? Diversity and Inclusion in STEM
Recently the halls of the White House were packed with science projects — robots, 3D-printed objects, computer programs, apps, and extraordinary scientific discoveries — all built, invented, designed, and brought to fruition by students.
Exhibits at the White House Science Fair Include: (More information can be found here.)
Teen uses Tech to Tackle Cyber-bullying (Trisha Prabhu, 14, Naperville, Illinois). Illinois teen Trisha Prabhu learned about research showing that the human brain’s decision-making region is not fully developed until age 25 and got inspired to help teens rethink how they treat others. She developed a computer program called “Rethink” that alerts users when an outgoing message contains language that is potentially abusive and hurtful. Preliminary analysis showed that adolescents who use “Rethink” system are 93% less likely to send abusive messages than those who are not warned about the consequences of their actions prior to sending a message. Trisha earned a spot in the 2014 Google Science Fair to showcase her innovative project.
Kaitlin Reed demonstrates to President Barack Obama the attachable lever she developed that can make wheelchair movements easier and less tiring. With Kaitlin is Mohammed Sayed, who developed a 3D-printed modular arm for his wheelchair that can be used as a food tray, camera tripod, rain canopy, laptop holder, and cup holder. The two 16-year-old students are from Massachusetts. (Official White House Photo by Pete Souza)
Scoliosis Patient Designs Implant to help Kids avoid Spinal Surgeries (Harry Paul, 18, Port Washington, NY). 18-year-old Harry Paul was born with congenital scoliosis, a curvature of the spine that, when congenital, restricts the size of the thorax preventing the heart and lungs from developing. Growing up, Harry endured more than a dozen spinal surgeries to help correct the problem. Now, he’s working to help other young people with scoliosis avoid the burdensome operations that can get in the way of living life. He designed a new type of spinal implant that expands over time, helping developing spines stay straighter as they grow, and lengthening the time young patients can go between surgeries. Harry’s implant could potentially help lower the number of risky procedures needed from over a dozen to less than five over the course of child’s surgical treatment. His design earned him numerous awards, including the Grand Awards of First Place, Best in Category (Bioengineering), and the Innovation Exploration Award at the 2014 Intel International Science and Engineering Fair.
Solar-Heating System Brings Warmth to Communities off the Grid (Kelly Charley, 15, Farmington, NM). Kelly Charley, 15, noticed that communities lacking electricity often build fires to stay warm, but that particles and ash from wood-burning fireplaces can be dangerous to breathe. She developed a solar-powered radiation system that circulates air and heats the interior of buildings. It can run without access to electricity or running water. Kelly, a sophomore at Navajo Preparatory School in Farmington, New Mexico, received a United National Indian Tribal Youth 25 under 25 Youth Leadership Award for her work to promote spiritual, mental, physical, and social well-being. Her heater design made her a finalist at the 2014 International Science and Engineering Fair.
Kid Inventor Designs Wearable Monitor for Grandfather with Alzheimer’s (Kenneth Shinozuka, 16
New York, NY). More than half of the 5.2 million Americans with Alzheimer’s wander, which can lead to injury or death. Kenneth Shinozuka became acutely aware of this problem while caring for his grandfather, who was afflicted with the disease. Kenneth developed a sensor device that can detect when a wanderer stands up, apply pressure on his or her foot, and send an alert to the caregiver’s smartphone via Bluetooth. During six months of use, the device detected every instance when Kenneth’s grandfather got out of bed at night, without any false positives, ensuring his whereabouts were always known. Kenneth’s device won the Science in Action award at the 2014 Google Science fair.Truly Flashy Fashion Accessories Use Tech to make Exercise Look Good (Maureen Botros, 15, Wichita, KS). Maureen Botros wants to make physical activity not just feel good, but also look good. Her invention, Illumi-cize, uses a pulse meter to measure heart rate and sends that information to a battery-powered computer chip. The chip is programmed to illuminate light-up accessories based on the intensity of a person’s physical activity. The wearable device includes a SD card that collects and stores the data gathered during a workout, which can be analyzed and tracked by the user. For those with more conservative styles, Maureen developed a less flashy wristband that can be programmed to shine red, yellow, or green to signal whether and how much person’s heart rate is elevated beyond its normal resting range. The invention took the top prize at the Kansas Junior Academy of Science competition and will be presented at the upcoming joint national meeting of the American Junior Academy of Sciences and the American Association for the Advancement of Science.