Congress Advances “Girls Count” Legislation
On May 23, the Senate approved, by unanimous consent, the Girls Count Act (S. 802). On May 21, the Senate Foreign Relations Committee and the House Foreign Affairs Committee approved their versions of the Girls Count Act, S. 802, and H.R. 2100, respectively.
Kay E. Brown, director, Education, Workforce, and Income Security, Government Accountability Office (GAO), described the fraud uncovered in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). * See page 3
The legislation, sponsored by Sen. Marco Rubio (R-FL) and Rep. Steve Chabot (R-OH), would authorize the secretary of State and the administrator of the United States Agency for International Development (USAID) to support programs that “contribute to improved civil registration and vital statistics systems with a focus on birth registration.” The bill finds that the lack of birth registration for girls can exacerbate women’s and girls’ vulnerability to trafficking, child marriage, lack of access to health and education services, reduced unemployment, and can inhibit their ability to purchase or inherit land and other assets, among many other issues.
The bill would “promote programs that build the capacity of developing countries’ national and local legal and policy frameworks to prevent discrimination against girls, and help increase property rights, social security, land tenure, and inheritance rights for women.” The measure also would authorize the secretary and the administrator to cooperate with multilateral organizations, such as the World Bank and the United Nations, to promote such programs.
The Senate Foreign Relations Committee approved S. 802, as amended by substitute amendment, by voice vote; the House Foreign Affairs Committee approved H.R. 2100 by voice vote.
House Committee Approves Commerce, Justice, Science Spending Bill
On May 20, the House Appropriations Committee approved, by voice vote, the FY2016 Commerce, Justice, Science, and Related Agencies spending bill (as-yet-unnumbered). The House Appropriations Subcommittee on Commerce, Justice, Science, and Related Agencies passed the measure on May 14 (see The Source, 5/15/15).
According to the committee report, the bill would allocate $51.4 billion overall for FY2016. This amount is $1.3 billion above FY2015, but $661 million below President Obama’s FY2016 request. Included in this amount is $27.5 billion for the Department of Justice (DoJ)
Citing increased instances of severe harassment, stalking, and threats transmitted via the Internet, particularly against women, the committee urges DoJ to increase its efforts to combat cyber-stalking and threat crimes (p. 31).
The committee” is concerned with the ongoing sexual assault kit backlog in jurisdictions across the country.” The bill includes $41 million in the bill to address the backlog (p. 41).
The committee encourages the Office for Victims of Crime and the Office of Juvenile Justice and Delinquency Prevention to examine ways to support nonprofits and other nongovernmental entities to administer successful prevention and early intervention programs for girls vulnerable to trafficking (p. 47).
Expressing its disappointment with recent Office of Inspector General (OIG) reports detailing sexual misconduct and harassment by Drug Enforcement Administration (DEA) agents while on overseas assignment, the committee noted that it expects the DEA and DoJ to “close the gaps” identified in the OIG report and address employee misconduct (p. 40).
The committee encourages the International Trade Administration to ensure that it is providing suitable support and services for women-, minority- and veteran-owned firms that are seeking aid in gaining access to foreign markets for their products and services (p. 5).
During the consideration of the measure, the committee adopted, by voice vote, two amendments by Rep. Debbie Wasserman Schultz (D-FL). The first amendment would add $5 million to the Department of Justice Rape Survivor Child Custody Act (P.L. 102-393) program to terminate rapists’ parental custodial rights. The second amendment would designate $1 million in funding within Missing and Exploited Children Program to hire wounded warriors to assist with these cases.
The following chart details funding for program important to women and their families.
A Memorial Day Scout Report: iWASwondering, EduBlogger, Freakonomics Radio, Plotly, WWI Visual History and a Darwin Manuscripts Tree
“Stars over Berlin and Tokyo will soon replace these factory lights reflected in the noses of planes at Douglas Aircraft’s Long Beach, Calif., plant. Women workers groom lines of transparent noses for deadly A-20 attack bombers.” Alfred Palmer, October 1942. 208-AA-352QQ-5. US National Archives and Records Administration
Science, Technology, Engineering and Math: Education for Global Leadership
This page from the US Department of Education lays out the case for STEM (Science, Technology, Engineering, and Math) education. Readers will likely be interested to learn that some STEM fields are predicted to increase by a third and more this decade. Still, only 16 percent of American high school seniors are proficient in math and interested in STEM careers, and the nation suffers from a paucity of qualified math and science teachers. These facts and others can be found here, in addition to a number of interesting links that will take readers around the web, from President Obama’s plan to expand STEM education to the site for The Committee on Science, Technology, Engineering, and Math Education. For readers who are interested in STEM education, there is much to ponder on this interesting site.
·http://www.abmc.gov/sites/default/files/interactive/interactive_files/WW1/index.html
This attractive and edifying map-based interactive from the American Battle Monuments Commission will serve as a support to educators teaching the First World War, and to anyone with an interest in how the war began, how it developed, and how it finally ended. The history is divided into seven periods, including The Pre-War Period, each year from 1914 to 1918, and the Post-War Years. Clicking on any of these will redraw the World War I Timeline, detailing important events, campaigns, and the ebb and flow of the Allied and Central Powers. For instance, within the Prewar Years, selecting The Triple Alliance navigates to a portrait of Otto von Bismarck and a short explanation of the shaky alliance that was formed between Germany, Austria-Hungary, and Italy in 1882 to fend off France. Short video clips accompany many of the Timeline items, bringing the history of the war to life.
The Edublogger, which serves as the community blog for Edublogs and CampusPress, is designed to help educational bloggers with emerging technologies in education. For readers who don’t blog about education, there is still plenty of usable content on the site. Recent posts have included a mini how-to course on infographics, tips for getting students engaged in their classes through blogging, and a story about standardized testing in Mexico. There is even a short video that introduces inexperienced readers to the wide world of blogging, as well as sections on Blogging Resources and Educator’s Guides. This site is recommended for anyone who wants to stay up-to-date on how Internet technologies can be integrated into the classroom.
·http://www.iwaswondering.org/
This website serves as a companion piece to the Women’s Adventures in Science biography series from the National Academy of Science. It begins with a short video featuring an upbeat and ever-curious character named Lia, and expands to provide the various and intriguing careers of some of today’s prominent female scientists, including Inez Fung and Amy Vedder. While the website and series are designed for middle-school-aged students, educators and parents can get behind the message: let’s get girls involved in science. In addition to 10 Cool Scientists, kids can ask their own questions and receive an answer from an expert, or play fun and interesting activities and games, like the AstroScope, an online astronomy game.
Bring Along the Sunscreen For That Sun-bathing Weekend: Cancer-associated DNA Changes Exist in 25% of Normal Skin Cells
Sunbathing in Boracay, Philippines
Using healthy skin to identify cancer’s origins
Normal skin contains an unexpectedly high number of cancer-associated mutations, according to a study published in Science. The findings illuminate the first steps cells take towards becoming a cancer and demonstrate the value of analysing normal tissue to learn more about the origins of the disease.
The study revealed that each cell in normal facial skin carries many thousands of mutations, mainly caused by exposure to sunlight. Around 25 per cent of skin cells in samples from people without cancer were found to carry at least one cancer-associated mutation.
Ultra-deep genetic sequencing was performed on 234 biopsies taken from four patients revealing 3,760 mutations, with more than 100 cancer-associated mutations per square centimetre of skin. Cells with these mutations formed clusters of cells, known as clones, that had grown to be around twice the size of normal clones, but none of them had become cancerous.
“With this technology, we can now peer into the first steps a cell takes to become cancerous,” explains Dr Peter Campbell, a corresponding author from the Wellcome Trust Sanger Institute. “These first cancer-associated mutations give cells a boost compared to their normal neighbors. They have a burst of growth that increases the pool of cells waiting for the next mutation to push them even further.
“We can even see some cells in normal skin that have taken two or three such steps towards cancer. How many of these steps are needed to become fully cancerous? Maybe five, maybe 10, we don’t know yet.”
The mutations observed showed the patterns associated with the most common and treatable form of skin cancer linked to sun exposure, known as cutaneous squamous cell carcinoma, rather than melanoma, a rarer and sometimes fatal form of skin cancer.
“The burden of mutations observed is high but almost certainly none of these clones would have developed into skin cancer,” explains Dr Iñigo Martincorena, first author from the Sanger Institute. “Because skin cancers are so common in the population, it makes sense that individuals would carry a large number of mutations. What we are seeing here are the hidden depths of the iceberg, not just the relatively small number that break through the surface waters to become cancer.”
Skin samples used in this study were taken from four people aged between 55 and 73 who were undergoing routine surgery to remove excess eyelid skin that was obscuring vision. The mutations had accumulated over each individual’s lifetime as the eyelids were exposed to sunshine. The researchers estimate that each sun-exposed skin cell accumulated on average a new mutation in its genome for nearly every day of life.
Sublclonal structure of a large clone found to overlap with six biopsies (purple areas on the eyelid – top). Mutant clones in an average 1 cm2 of normal eyelid skin. [DOI: 10.1126/science.aaa6806]
“These kinds of mutations accumulate over time – whenever our skin is exposed to sunlight, we are at risk of adding to them,” explains Dr Phil Jones, a corresponding author from the Sanger Institute and the MRC Cancer Unit at the University of Cambridge. “Throughout our lives we need to protect our skin by using sun-block lotions, staying away from midday sun and covering exposed skin wherever possible. These precautions are important at any stage of life but particularly in children, who are busy growing new skin, and older people, who have already built up an array of mutations.”
Recent studies analysing blood samples from people who do not have cancer had revealed a lower burden of mutations, with only a small percentage of individuals carrying a cancer-causing mutation in their blood cells. Owing to sun exposure, skin is much more heavily mutated, with thousands of cancer-associated mutations expected in any adult’s skin.
The results demonstrate the potential of using normal tissue to better understand the origins of cancer. The Cancer Genomics group at the Sanger Institute will continue this work with larger sample numbers and a broader range of tissues to understand how healthy cells transition into cancerous cells.
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High burden and pervasive positive selection of somatic mutations in normal human skin.
Science 2015